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An annexin A1–FPR1 interaction contributes to necroptosis of keratinocytes in severe cutaneous adverse drug reactions

Authors :
Saito, Nao
Qiao, Hongjiang
Yanagi, Teruki
Shinkuma, Satoru
Nishimura, Keiko
Suto, Asuka
Fujita, Yasuyuki
Suzuki, Shotaro
Nomura, Toshifumi
Nakamura, Hideki
Nagao, Koji
Obuse, Chikashi
Shimizu, Hiroshi
Abe, Riichiro
Source :
Science Translational Medicine; July 2014, Vol. 6 Issue: 245 p245ra95-245ra95, 1p
Publication Year :
2014

Abstract

Annexin A1 secreted from drug-stimulated monocytes contributes to keratinocyte necroptosis in serious drug-related adverse events in skin.

Details

Language :
English
ISSN :
19466234 and 19466242
Volume :
6
Issue :
245
Database :
Supplemental Index
Journal :
Science Translational Medicine
Publication Type :
Periodical
Accession number :
ejs33335435
Full Text :
https://doi.org/10.1126/scitranslmed.3008227