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BK Polyomavirus‐Specific Cellular Immune Responses Are Age‐Dependent and Strongly Correlate With Phases of Virus Replication

Authors :
Schmidt, T.
Adam, C.
Hirsch, H. H.
Janssen, M. W. W.
Wolf, M.
Dirks, J.
Kardas, P.
Ahlenstiel‐Grunow, T.
Pape, L.
Rohrer, T.
Fliser, D.
Sester, M.
Sester, U.
Source :
American Journal of Transplantation; June 2014, Vol. 14 Issue: 6 p1334-1345, 12p
Publication Year :
2014

Abstract

The authors characterize BK virus–specific cellular and humoral immunity in immunocompetent controls across a wide age range and in renal transplant recipients, and show that the level of immunity reflects phases of active viral replication either after primary infection in childhood or during reactivation after transplantation.

Details

Language :
English
ISSN :
16006135 and 16006143
Volume :
14
Issue :
6
Database :
Supplemental Index
Journal :
American Journal of Transplantation
Publication Type :
Periodical
Accession number :
ejs32889884
Full Text :
https://doi.org/10.1111/ajt.12689