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Heps with Pep: Direct Reprogramming into Human Hepatocytes
- Source :
- Cell Stem Cell; March 2014, Vol. 14 Issue: 3 p267-269, 3p
- Publication Year :
- 2014
-
Abstract
- The limited supply and expansion capacity of primary human hepatocytes presents major challenges for pharmaceutical applications and development of cell-based therapies for liver diseases. Now in Cell Stem Cell, two papers demonstrate efficient direct reprogramming of human fibroblasts into induced hepatocytes, which exhibit metabolic properties similar to primary hepatocytes.
Details
- Language :
- English
- ISSN :
- 19345909
- Volume :
- 14
- Issue :
- 3
- Database :
- Supplemental Index
- Journal :
- Cell Stem Cell
- Publication Type :
- Periodical
- Accession number :
- ejs32323500
- Full Text :
- https://doi.org/10.1016/j.stem.2014.02.010