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A Factor XIIa Inhibitory Antibody Provides Thromboprotection in Extracorporeal Circulation Without Increasing Bleeding Risk
- Source :
- Science Translational Medicine; February 2014, Vol. 6 Issue: 222 p222ra17-222ra17, 1p
- Publication Year :
- 2014
-
Abstract
- Blocking the enzyme that initiates the intrinsic coagulation pathway protects against thrombosis in bypass systems and does not cause excess bleeding in vivo.
Details
- Language :
- English
- ISSN :
- 19466234 and 19466242
- Volume :
- 6
- Issue :
- 222
- Database :
- Supplemental Index
- Journal :
- Science Translational Medicine
- Publication Type :
- Periodical
- Accession number :
- ejs32082599
- Full Text :
- https://doi.org/10.1126/scitranslmed.3006804