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Mechanism of Sensitization to UV Radiation by 5‐Br‐Uracil Substituted DNA

Authors :
Lion, M.
Source :
Israel Journal of Chemistry; 1972, Vol. 10 Issue: 6 p1151-1163, 13p
Publication Year :
1972

Abstract

DNA, in which thymine is substituted by 5‐bromouracil is sensitized to the effect of ultraviolet light. Various chemical changes produced in the DNA are described. These include single and double strand breaks, base loss, protein DNA crosslinks as well as the influence of the three dimensional structure of DNA on some of these changes.

Details

Language :
English
ISSN :
00212148 and 18695868
Volume :
10
Issue :
6
Database :
Supplemental Index
Journal :
Israel Journal of Chemistry
Publication Type :
Periodical
Accession number :
ejs31501363
Full Text :
https://doi.org/10.1002/ijch.197200121