Phytochemical Screening and Anti-Inflammatory Actions of Alangium villosum polyosmoidesRoot Extract

AbstractThe purpose of the present study was to explore phytochemical characteristics and to investigate the anti-inflammatory actions of the methanolic extract of Alangium villosum polyosmoidesroots. A. villosum polyosmoidesroots were characterized for phytochemical and the percentage inhibition of carrageenan induced paw oedema was studied in rats. A. villosum polyosmoidesgave maximum extractive values with Methanol and the Loss on Drying value, total Ash value, acid-insoluble ash, water soluble ash values were within limits. The extract gave positive tests for Phytosterols, Triterpenes, Flavonoids, Carbohydrates and Alkaloids. The extract was free from Glycosides, Saponins, Tannins, Proteins and Amino Acids. The A. villosum polyosmoidesroot gave significant per cent inhibition of the maximal paw Oedema and very highly significant per cent inhibition of total paw Oedema during 6 h. This study revealed that A. villosum polyosmoidesroot has good anti-inflammatory actions when compared with Diclofenac sodium.