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Monoclonal antibody differentiates chicken Asystem alloantigens*

Authors :
FULTON, J. E.
BRILES, R. W.
LAMONT, S. J.
Source :
Animal Genetics; February 1990, Vol. 21 Issue: 1 p39-45, 7p
Publication Year :
1990

Abstract

SummaryA monoclonal antibody (ISU‐cA) was produced that recognized certain alloantigens of the chicken Ablood group locus. Antigens produced by alleles A3, A4and A8were positive, and those produced by A2and A5were negative, by haemagglutination. The specificity of ISU‐cA for chicken A blood group antigens was demonstrated by serologic analyses, genetic crosses and competitive inhibition of binding by anti‐A alloantisera. To our knowledge, this is the first reported monoclonal antibody against a chicken blood group alloantigen system other than the Bcomplex.

Details

Language :
English
ISSN :
02689146 and 13652052
Volume :
21
Issue :
1
Database :
Supplemental Index
Journal :
Animal Genetics
Publication Type :
Periodical
Accession number :
ejs30767232
Full Text :
https://doi.org/10.1111/j.1365-2052.1990.tb03205.x