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INTRAMUSCULAR USE OF DIMENHYDRINATE (DRAMAMINE) TO CONTROL POSTOPERATIVE VOMITING

INTRAMUSCULAR USE OF DIMENHYDRINATE (DRAMAMINE) TO CONTROL POSTOPERATIVE VOMITING

Authors :
Moore, Daniel C.
Bridenbaugh, L. Donald
Green, John C.
Piccioni, Vincent F.
Adams, Pliny A.
Lindstrom, Carl A.
Source :
JAMA: Journal of the American Medical Association; December 1955, Vol. 159 Issue: 14 p1342-1345, 4p
Publication Year :
1955

Abstract

In November, 1951, we presented a paper in which it was stated that intramuscularly administered dimenhydrinate (Dramamine) seemed to reduce postoperative vomiting by approximately 50%. At that time it was stated, "It is hoped that further interest in this subject will be stimulated so that an extensive evaluation of the drug may be made."1 Certain objections have been raised regarding the validity of the conclusions of our preliminary report and those of others describing the efficacy of dimenhydrinate for control of postoperative vomiting.2 The main objections that have been raised were that (1) if the study method described in this article is to be significant, many thousands of cases must be reported, and (2) no "placebo" control series appeared. Other minor objections included the facts that ( 1) there was no note made of the amount of vomiting past 50 cc., which was set as criterion for vomiting; (2)

Details

Language :
English
ISSN :
00987484 and 15383598
Volume :
159
Issue :
14
Database :
Supplemental Index
Journal :
JAMA: Journal of the American Medical Association
Publication Type :
Periodical
Accession number :
ejs28775699
Full Text :
https://doi.org/10.1001/jama.1955.02960310006005