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The Ultrastructure of Human Organ-Cultured Cornea: I. Endothelium
- Source :
- Archives of Ophthalmology; December 1974, Vol. 92 Issue: 6 p516-523, 8p
- Publication Year :
- 1974
-
Abstract
- Human corneal endothelial cells maintained ultrastructural integrity after organ culture storage at 37 C for 10 to 21 days. Those organ-cultured corneas with postmortem times less than 12 hours had a complete layer of ultrastructurally intact endothelial cells of normal thickness and diameter. When postmortem times were longer than 24 hours, there was a complete layer of ultrastructurally intact endothelial cells that were large in diameter and thin. Control fellow corneas in moist chamber storage at 4 C demonstrated endothelial cell disruption proportional in area and severity to postmortem time duration. This implies that a dynamic process of endothelial repair, presumably by enlargement of remaining viable cells, occurs in organ culture.
Details
- Language :
- English
- ISSN :
- 00039950 and 15383601
- Volume :
- 92
- Issue :
- 6
- Database :
- Supplemental Index
- Journal :
- Archives of Ophthalmology
- Publication Type :
- Periodical
- Accession number :
- ejs28576930
- Full Text :
- https://doi.org/10.1001/archopht.1974.01010010530015