Multimodality visualization of medical volume data

New developments in 3-D volume acquisitions are creating a rapidly increasing demand for integrating multimodality 3-D visualization. In order to accomplish routine clinical multimodality visualization, many issues have to be dealt with, such as techniques for accurate spatial registration, integrated representation, suitable graphical user interfaces, and obtaining adequate rendering speeds. The aim of this experience paper is 2-fold. First, it presents various results from our research on multimodality visualization/registration. Second, this paper explicitly addresses practical problems and findings related to software development and multimodality registration/visualization. We hope that this will give colleagues a better understanding in some of these issues based on our experience, including notably our mistakes.