An efficient protocol for acetalization of carbonyl compounds using Zr(HSO4)4 at room temperature under solvent-free conditions

Abstract: Zr(HSO₄)₄ as a solid acid was applied for the acetalization of carbonyl compounds, at room temperature, under solvent-free conditions with good to excellent yields. The low cost and availability of the reagents, versatile procedure and easy work-up make this method attractive for the organic synthesis of these compounds.