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Insights into Airway Infections by Enterococci: A Review

Authors :
Savini, Vincenzo
Gherardi, Giovanni
Astolfi, Daniela
Polilli, Ennio
Dicuonzo, Giordano
D'Ama, Claudio
Source :
Recent Patents on Anti-Infective Drug Discovery; 2012, Vol. 7 Issue: 1 p36-44, 9p
Publication Year :
2012

Abstract

Enterococcus is an uncommon but emerging agent of upper and lower airway diseases, including sinuses, trachea, bronchi, lung and pleural infections. In particular, pneumonia and thoracic empyema may jeopardize the clinical outcome of compromised, hospitalized hosts, as well as affect outpatients. Treatment may feel the effects of inherent and acquired resistances such organisms show to commonly used drugs, with the spread of glycopeptide/vancomycin resistant enterococci (GRE/VRE, respectively) being of serious concern. With this work, we want to unearth the impact of members of the genus in the ambit of respiratory infections, and to increase the consciousness of their role as resourceful pathogens for human airways. Also, we are revising patents of interest aiming to timely screen GRE and soon provide clinicians with speciation and glycopeptide resistances.

Details

Language :
English
ISSN :
1574891X
Volume :
7
Issue :
1
Database :
Supplemental Index
Journal :
Recent Patents on Anti-Infective Drug Discovery
Publication Type :
Periodical
Accession number :
ejs26987192