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Bystander apoptosis in human cells mediated by irradiated blood plasma

Authors :
Vinnikov, Volodymyr
Lloyd, David
Finnon, Paul
Source :
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis; March 2012, Vol. 731 Issue: 1-2 p107-116, 10p
Publication Year :
2012

Abstract

► A bystander cytotoxic effect of plasma from irradiated human blood was assessed. ► Irradiated blood plasma did not cause apoptosis in unirradiated reporter leucocytes. ► But a plasma-induced reduction of apoptosis was found in irradiated reporter cells. ► The protective bystander effect can increase an oncogenic risk after radiotherapy.

Details

Language :
English
ISSN :
13861964
Volume :
731
Issue :
1-2
Database :
Supplemental Index
Journal :
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis
Publication Type :
Periodical
Accession number :
ejs26709586
Full Text :
https://doi.org/10.1016/j.mrfmmm.2011.12.006