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A Common Mutation in the Defensin DEFB126Causes Impaired Sperm Function and Subfertility
- Source :
- Science Translational Medicine; July 2011, Vol. 3 Issue: 92 p92ra65-92ra65, 1p
- Publication Year :
- 2011
-
Abstract
- A frequent frameshift mutation in defensin DEFB126, a protein that adheres to the surface of human sperm, weakens its ability to penetrate cervical mucus-like gels and causes low fertility.
Details
- Language :
- English
- ISSN :
- 19466234 and 19466242
- Volume :
- 3
- Issue :
- 92
- Database :
- Supplemental Index
- Journal :
- Science Translational Medicine
- Publication Type :
- Periodical
- Accession number :
- ejs25460097
- Full Text :
- https://doi.org/10.1126/scitranslmed.3002289