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Preliminary X-Ray Crystallographic Studies of a Lys49-Phospholipase A2 Homologue from Bothrops pirajai Venom Complexed with p-Bromophenacyl Bromide and -Tocopherol Inhibitors
- Source :
- Protein and Peptide Letters; July 2007, Vol. 14 Issue: 7 p698-701, 4p
- Publication Year :
- 2007
-
Abstract
- PrTX-I, a non-catalytic and myotoxic Lys49-PLA2 from Bothrops pirajai venom has been crystallized alone and in complex with bromophenacyl bromide (BPB), -tocopherol and -tocopherol acetate inhibitors. These crystals have shown to diffract X-rays between 2.34 and 1.65 Å resolution. All complexes crystals are isomorphous and belong to the space group P21 whereas native PrTX-I crystals belong to the P3121.
Details
- Language :
- English
- ISSN :
- 09298665
- Volume :
- 14
- Issue :
- 7
- Database :
- Supplemental Index
- Journal :
- Protein and Peptide Letters
- Publication Type :
- Periodical
- Accession number :
- ejs25401804