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DNA complementary to parathyroid mRNA directs synthesis of pre-proparathyroid hormone in a linked transcription—translation system
- Source :
- Nature; June 1977, Vol. 267 Issue: 5614 p804-807, 4p
- Publication Year :
- 1977
-
Abstract
- DNA complementary in sequence to the messenger RNA for pre-proparathyroid hormone was synthesised using reverse transcriptase. In a linked transcription–translation system using RNA polymerase and cell-free extract from wheat germ, the DNA directed the synthesis of a protein identified as pre-proparathyroid hormone by N-terminal Sequencing and by electrophoretic and immunologic criteria.
Details
- Language :
- English
- ISSN :
- 00280836 and 14764687
- Volume :
- 267
- Issue :
- 5614
- Database :
- Supplemental Index
- Journal :
- Nature
- Publication Type :
- Periodical
- Accession number :
- ejs25226481
- Full Text :
- https://doi.org/10.1038/267804a0