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Association between suicide attempts and 5-HTTLPR-S-Allele in alcohol-dependent and control subjects: further evidence from a german alcohol-dependent inpatient sample
- Source :
- Biological Psychiatry; October 2001, Vol. 50 Issue: 8 p636-639, 4p
- Publication Year :
- 2001
-
Abstract
- Background: Genetically-mediated alterations in serotonergic transmission have been implicated in both the pathogenesis of alcoholism and suicidal behavior. Thus, the identification of vulnerability genes could uncover pathophysiological links for both syndromes. A significant association between suicide attempts and the 5-HTT promoter polymorphisms (5-HTTLPR) S-allele has been reported in a sample of French alcohol-dependent subjects, and this paper evaluates this phenomenon in a German sample.
Details
- Language :
- English
- ISSN :
- 00063223 and 18732402
- Volume :
- 50
- Issue :
- 8
- Database :
- Supplemental Index
- Journal :
- Biological Psychiatry
- Publication Type :
- Periodical
- Accession number :
- ejs2409196
- Full Text :
- https://doi.org/10.1016/S0006-3223(01)01196-9