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A “Neck‐Formation” Strategy for an Antiquenching Magnetic/Upconversion Fluorescent Bimodal Cancer Probe

Authors :
Chen, Feng
Zhang, Shengjian
Bu, Wenbo
Liu, Xiaohang
Chen, Yu
He, Qianjun
Zhu, Min
Zhang, Lingxia
Zhou, Liangping
Peng, Weijun
Shi, Jianlin
Source :
Chemistry - A European Journal; October 2010, Vol. 16 Issue: 37 p11254-11260, 7p
Publication Year :
2010

Abstract

Up to the neck!Bio‐safe upconversion fluorescent nanocrystals (NaYF4:Er,Yb) and biocompatible superparamagnetic iron oxide nanocrystals (SPION) were effectively combined by means of a general “neck‐formation” strategy, forming a size‐controlled, Cd2+‐ and Gd3+‐free, silica‐shielded, magnetic upconversion fluorescent oligomer (SMUFO), bimodal cancer probe that offers high resistance to photoquenching as well as a synergistic T2‐weighted magnetic resonance enhanced effect (see graphic).

Details

Language :
English
ISSN :
09476539 and 15213765
Volume :
16
Issue :
37
Database :
Supplemental Index
Journal :
Chemistry - A European Journal
Publication Type :
Periodical
Accession number :
ejs22692523
Full Text :
https://doi.org/10.1002/chem.201000525