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Highly Enantioselective Michael Addition Reactions of 3Substituted Benzofuran23Hones to Chalcones Catalyzed by a Chiral AlkylSubstituted Thiourea

Authors :
Li, Xin
Xi, Zhiguo
Luo, Sanzhong
Cheng, JinPei
Source :
Advanced Synthesis & Catalysis; May 2010, Vol. 352 Issue: 7 p1097-1101, 5p
Publication Year :
2010

Abstract

A highly enantioselective Michael addition of 3substituted benzofuran23Hones to chalcones catalyzed by a chiral bifunctional thiourea was developed. Several chiral 3,3′substituted benzofuran23Hones derivatives, bearing adjacent quaternarytertiary stereocenters, were efficiently synthesized with excellent enantioselectivities.

Details

Language :
English
ISSN :
16154150 and 16154169
Volume :
352
Issue :
7
Database :
Supplemental Index
Journal :
Advanced Synthesis & Catalysis
Publication Type :
Periodical
Accession number :
ejs21433409
Full Text :
https://doi.org/10.1002/adsc.201000106