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Chiral Bis(oxazolinyl)phenyl RuIICatalysts for Highly Enantioselective Cyclopropanation
- Source :
- Chemistry - A European Journal; May 2010, Vol. 16 Issue: 17 p4986-4990, 5p
- Publication Year :
- 2010
-
Abstract
- Good to excellent enantioselectivities(up to 99 % ee) of trans‐cyclopropane derivatives were achieved in the cyclopropanation of alkenes with tert‐butyl α‐diazoacetate by using 0.5 mol % of a mononuclear chiral ruthenium aqua complex containing the chiral bis(oxazolinyl)phenyl ligand, which was obtained via CH activation by RuCl3⋅3 H2O in the presence of Mg and cyclooctadiene (cod). Intramolecular cyclopropanation reactions using the new Ru complex also proceed with high yields and excellent enantioselectivities.
Details
- Language :
- English
- ISSN :
- 09476539 and 15213765
- Volume :
- 16
- Issue :
- 17
- Database :
- Supplemental Index
- Journal :
- Chemistry - A European Journal
- Publication Type :
- Periodical
- Accession number :
- ejs21239523
- Full Text :
- https://doi.org/10.1002/chem.200903514