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Synthesis and Notable Antimalarial Activity of Acyclic Peroxides, 1-(Alkyldioxy)-1-(methyldioxy)cyclododecanes
- Source :
- Journal of Medicinal Chemistry; March 2002, Vol. 45 Issue: 6 p1374-1378, 5p
- Publication Year :
- 2002
-
Abstract
- Of several bis(alkyldioxy)alkanes and the related acyclic peroxides prepared in this study, 1,1-bis(methyldioxy)cyclododecane showed the most notable antimalarial activity particularly in vivo (almost a half of that of artemisinin).
Details
- Language :
- English
- ISSN :
- 00222623 and 15204804
- Volume :
- 45
- Issue :
- 6
- Database :
- Supplemental Index
- Journal :
- Journal of Medicinal Chemistry
- Publication Type :
- Periodical
- Accession number :
- ejs2042212
- Full Text :
- https://doi.org/10.1021/jm010473w