Typhoid Fever in Group Travelers: Opportunity for Studying Vaccine Efficacy

Background: Typhoid fever (TF) is a rare disease among travelers to endemic areas, and little is known about its travel‐related epidemiology. In addition, efficacy data on TF vaccines in travelers is scanty. During 3 months of 1994/95, six cases of TF were reported in The Netherlands among participants of four package tours to Indonesia provided by the same operator. The present study was designed to describe the epidemiology of TF in these groups, and to assess whether travel groups can be used for studying the efficacy of TF vaccines in travelers.