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A novel rearrangement of the human {beta}like globin gene cluster

Authors :
Trent, R.J.
Bowden, D.K.
Old, J.M.
Wainscoat, J.S.
Clegg, J.B.
Weatherall, D.J.
Source :
Nucleic Acids Research; December 1981, Vol. 9 Issue: 24 p6723-6723, 1p
Publication Year :
1981

Abstract

The first example of a duplication involving the human β-like globin genes has been characterised in DNA from a native of Vanuatu. Restriction endonuclease mapping has shown that a 5 kb insert of DNA in the γ-δ-β gene cluster is due to duplication of the G<inf>γ</inf>-globin gene and results in a new rearrangement ‘5′-ɛ-Gγ-G<inf>γ</inf>-A<inf>γ</inf>-δ-β-3’

Details

Language :
English
ISSN :
03051048 and 13624962
Volume :
9
Issue :
24
Database :
Supplemental Index
Journal :
Nucleic Acids Research
Publication Type :
Periodical
Accession number :
ejs18582751
Full Text :
https://doi.org/10.1093/nar/9.24.6723