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D‐Fructose‐6‐phosphate Aldolase in Organic Synthesis: Cascade Chemical‐Enzymatic Preparation of Sugar‐Related Polyhydroxylated Compounds
- Source :
- Chemistry - A European Journal; April 2009, Vol. 15 Issue: 15 p3808-3816, 9p
- Publication Year :
- 2009
-
Abstract
- D‐Fructose‐6‐phosphate aldolase (FSA) is a key biocatalystfor the alternative synthetic construction of biologically active products with known therapeutic and research interest or novel structures relevant to drug discovery. Novel aldol addition reactions of dihydroxyacetone and hydroxyacetone to a variety of aldehydes catalyzed by FSA are presented (see scheme).
Details
- Language :
- English
- ISSN :
- 09476539 and 15213765
- Volume :
- 15
- Issue :
- 15
- Database :
- Supplemental Index
- Journal :
- Chemistry - A European Journal
- Publication Type :
- Periodical
- Accession number :
- ejs18344359
- Full Text :
- https://doi.org/10.1002/chem.200802532