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In vitro kinetics of the oxidative reactivity of nitrate and nitrite in the rat erythrocyte
- Source :
- Food Additives & Contaminants Part A; 1990, Vol. 7 Issue: Supplement 1 p145-149, 5p
- Publication Year :
- 1990
-
Abstract
- Isolated rat erythrocytes were incubated in the presence of nitrate and nitrite. Glucose, lactate, reduced glutathione, methaemoglobin, malondialdehyde and Na+/K+ membrane exchange were investigated. Nitrite induced a strong methaemoglobinaemia and a net depletion of reduced glutathione in the intracellular medium associated with membrane lipid peroxidation. This oxidative reactivity induced by nitrate and nitrite altered the cell's ionic flux.
Details
- Language :
- English
- ISSN :
- 19440049 and 19440057
- Volume :
- 7
- Issue :
- Supplement 1
- Database :
- Supplemental Index
- Journal :
- Food Additives & Contaminants Part A
- Publication Type :
- Periodical
- Accession number :
- ejs17703281
- Full Text :
- https://doi.org/10.1080/02652039009373868