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Cartilage oligomeric matrix protein deficiency promotes early onset and the chronic development of collagen-induced arthritis

Authors :
Geng, Hui
Carlsen, Stefan
Nandakumar, Kutty
Holmdahl, Rikard
Aspberg, Anders
Oldberg, Åke
Mattsson, Ragnar
Source :
Arthritis Research & Therapy (formerly Arthritis Research); December 2008, Vol. 10 Issue: 6 pR134-R134, 1p
Publication Year :
2008

Abstract

Cartilage oligomeric matrix protein (COMP) is a homopentameric protein in cartilage. The development of arthritis, like collagen-induced arthritis (CIA), involves cartilage as a target tissue. We have investigated the development of CIA in COMP-deficient mice.

Details

Language :
English
ISSN :
14786354 and 14786362
Volume :
10
Issue :
6
Database :
Supplemental Index
Journal :
Arthritis Research & Therapy (formerly Arthritis Research)
Publication Type :
Periodical
Accession number :
ejs17472578
Full Text :
https://doi.org/10.1186/ar2551