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Changes in gentamicin pharmacokinetics after reduction of renal parenchyma

Authors :
Schück, O.
Morávek, J.
Hatala, M.
Source :
Experientia; August 1977, Vol. 33 Issue: 8 p1075-1076, 2p
Publication Year :
1977

Abstract

The relationship between the elimination constant of gentamicin and the percentage of functioning nephrons in rats cannot be characterized by a simple linear relation. The results support the assumption that gentamicin elimination per residual nephron increased.

Details

Language :
English
ISSN :
00144754
Volume :
33
Issue :
8
Database :
Supplemental Index
Journal :
Experientia
Publication Type :
Periodical
Accession number :
ejs16520067
Full Text :
https://doi.org/10.1007/BF01945978