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Maternal immunization by husband's leukocytes for repeated fetal death associated with mild pre-eclampsia — case report with successful outcome
- Source :
- Archives of Gynecology and Obstetrics; December 1992, Vol. 252 Issue: 2 p103-107, 5p
- Publication Year :
- 1992
-
Abstract
- We report a case of repeated fetal death at 31 gestational weeks associated with mild non-proteinuric pre-eclampsia and intrauterine growth retardation. After double intradermal immunisation with paternal leukocytes, a third pregnancy proceeded uneventfully until it ended at 38 weeks. Maternal anti-paternal blocking antibody activity was assessed by the erythrocyte antibody inhibition (EAI) test. Serologic testing revealed that the couple did not share HLA class I antigens. The mechanisms underlying the likely benefit from immunotherapy are discussed.
Details
- Language :
- English
- ISSN :
- 09320067 and 14320711
- Volume :
- 252
- Issue :
- 2
- Database :
- Supplemental Index
- Journal :
- Archives of Gynecology and Obstetrics
- Publication Type :
- Periodical
- Accession number :
- ejs16370510
- Full Text :
- https://doi.org/10.1007/BF02389636