Käsig-tuberkuloide Reaktion bei Lymphknotenmetastasen lymphoepithelialer Carcinome (Schmincke-Tumoren)

Among 42 cases of lymph node metastases of lymphoepithelial carcinoma (Schmincke-Régaud) there were 5 which also showed an epithelioid cell reaction with varying amounts of caseous necrosis. These tuberculoid changes occur only together with carcinomatous infiltration of the lymph nodes themselves; in neighboring lymph nodes which have not been infiltrated by carcinoma cells only epithelioid cell reactions without caseous necroses are seen. These are considered to be tuberculoid reactions to the tumor necroses, while the caseous necroses are to be considered, at least partly, as necrotic tumor complexes. The epithelioid cell reaction with caseous necroses appears almost exclusively as a consequence of Schmincke tumors, occasionally long before the primary tumor is discovered.