Back to Search Start Over

Detection of Epstein-Barr virus in a case of undifferentiated nasopharyngeal carcinoma by in situ hybridization with digoxigenin-labelled PCR-generated probes

Authors :
Delvenne, P.
Kaschten, B.
Deneufbourg, J. M.
Demanez, L.
Stevenaert, A.
Reznik, M.
Boniver, J.
Source :
Virchows Archiv; March 1993, Vol. 423 Issue: 2 p145-150, 6p
Publication Year :
1993

Abstract

A case of nasopharyngeal carcinoma is presented. Epstein-Barr viral genome was identified in the neoplastic cells by in situ hybridization with digoxigeninlabelled polymerase chain reaction-generated probes. We report the development of this technique in paraffinembedded sections and propose that such identification may prove valuable for the diagnosis of this tumour in routine material.

Details

Language :
English
ISSN :
09456317 and 14322307
Volume :
423
Issue :
2
Database :
Supplemental Index
Journal :
Virchows Archiv
Publication Type :
Periodical
Accession number :
ejs16351340
Full Text :
https://doi.org/10.1007/BF01606589