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The kinetics of human glioblastomas maintained in an organ culture system
- Source :
- Acta Neuropathologica; March 1983, Vol. 61 Issue: 1 p1-9, 9p
- Publication Year :
- 1983
-
Abstract
- Five human glioblastomas maintained in an organ culture system were studied by autoradiography to determine, after 8 days in vitro, the growth fraction (GF) of the explants, their total cell cycle time (T<subscript>C</subscript>) and cell cycle phase durations (T<subscript>S</subscript>,T<subscript>G1</subscript>,T<subscript>G2</subscript> andT<subscript>M</subscript>), and their potential doubling time (T<subscript>pot</subscript>) after pulse-labeling with [<superscript>3</superscript>H] TdR for 1 h. These parameters were derived from computer analysis of fraction of labeled mitoses (FLM) curves. The results fell into two groups.
Details
- Language :
- English
- ISSN :
- 00016322 and 14320533
- Volume :
- 61
- Issue :
- 1
- Database :
- Supplemental Index
- Journal :
- Acta Neuropathologica
- Publication Type :
- Periodical
- Accession number :
- ejs16166862
- Full Text :
- https://doi.org/10.1007/BF00688379