The behavior of worker and non-worker rats under the influence of (−) δ9-trans-tetrahydrocannabinol, chlorpromazine and amylobarbitone

The effects of ?⁹-THC, chlorpromazine and amylobarbitone on the labor division achieved by rats were studied. While the first two drugs in the doses of, respectively, 5.0 and 3.0 mg/kg, induced an inversion in the social pattern, amylobarbitone was ineffective at doses of 10.0 and 20.0 mg/kg; labor division of rats trained under a CRF was more sensitive to the drugs effects than that of animals under a VI schedule of reinforcement. Results were discussed in terms of a drug induced deconditioning effect without loss of motivation.