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Die Bedeutung der Monoaminoxydasehemmung als antidepressives Prinzip. II

Authors :
Praag, H. M.
Leijnse, B.
Source :
Psychopharmacology; March 1963, Vol. 4 Issue: 2 p91-102, 12p
Publication Year :
1963

Abstract

The effect of some MAO-inhibiting hydrazines on the metabolism of exogenous 5-HT was investigated in 18 patients. These drugs were found to reduce the production of 5-HIAA after oral administration of 5-HT. This phenomenon was not in any way correlated with the development of the psychical changes. Moreover, it is probably not brought about by blockage of MAO activity. A few alternatives to inhibition of MAO activity are discussed.

Details

Language :
English
ISSN :
00333158 and 14322072
Volume :
4
Issue :
2
Database :
Supplemental Index
Journal :
Psychopharmacology
Publication Type :
Periodical
Accession number :
ejs16017153
Full Text :
https://doi.org/10.1007/BF00413327