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Efficacy and safety of the combination therapy Pilogel®/β-blocker: Interim results
- Source :
- Documenta Ophthalmologica; August 1989, Vol. 72 Issue: 3-4 p391-398, 8p
- Publication Year :
- 1989
-
Abstract
- The interim results of a multicentered clinical trial with the combination therapy Pilogel<superscript>®</superscript>/topical ß-blocker (twice daily) in patients with primary open angle glaucoma or ocular hypertension are discussed. Six patients were treated with Pilogel<superscript>®</superscript> and a topical ß-blocker for one month. Four out of six patients responded well to the combination therapy. Most patients experienced some difficulty in applying the gel and their eyelids stuck together on awakening. In two patients a superficial punctate keratitis was observed. We found an average decrease in intra-ocular pressure (IOP) of 22.5% 22.5 hours after Pilogel<superscript>®</superscript> administration, but there was some tendency towards higher evening values compared to morning values. In view of the appearance of a corneal haze as described by Johnson et al. during long-term treatment, longer follow-up is necessary.
Details
- Language :
- English
- ISSN :
- 00124486 and 15732622
- Volume :
- 72
- Issue :
- 3-4
- Database :
- Supplemental Index
- Journal :
- Documenta Ophthalmologica
- Publication Type :
- Periodical
- Accession number :
- ejs15324838
- Full Text :
- https://doi.org/10.1007/BF00153508