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Arachidonic acid aggregates neutrophils

Authors :
O'Flaherty, J. T.
Showell, H. S.
Becker, E. L.
Ward, P. A.
Source :
Inflammation; September 1979, Vol. 3 Issue: 4 p431-436, 6p
Publication Year :
1979

Abstract

Arachidonic acid, but not several structurally similar fatty acids, stimulated neutrophils in suspension to aggregate; this effect was blocked by 5,8,11,14-eicosatetraynoic acid, an inhibitor of arachidonic acid metabolism. Analagous to platelets, arachidonate may be a precursor of active metabolites which mediate neutrophil responses.

Details

Language :
English
ISSN :
03603997 and 15732576
Volume :
3
Issue :
4
Database :
Supplemental Index
Journal :
Inflammation
Publication Type :
Periodical
Accession number :
ejs15029429
Full Text :
https://doi.org/10.1007/BF00913500