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Microtubules and Commuting Receptors
- Source :
- Letters in Drug Design & Discovery; October 2006, Vol. 3 Issue: 8 p567-568, 2p
- Publication Year :
- 2006
-
Abstract
- Receptors that undergo nucleo-cytoplasmic shuttling require microtubules for proper physiologic function. Is it the collapse of microtubules network or simply the arrest of cell cycle in G2/M phase that changes receptors function? The terms of disengagement and the integrity versus dynamics of the microtubules shall guide the ideal drug design.
Details
- Language :
- English
- ISSN :
- 15701808
- Volume :
- 3
- Issue :
- 8
- Database :
- Supplemental Index
- Journal :
- Letters in Drug Design & Discovery
- Publication Type :
- Periodical
- Accession number :
- ejs14720078