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Synthesis and Interactions with Blood of Polyetherure-Thaneurea/Polypeptide Block Copolymers
- Source :
- Artificial Cells, Blood Substitutes, and Biotechnology; 1993, Vol. 21 Issue: 4 p571-580, 10p
- Publication Year :
- 1993
-
Abstract
- Polyurethane/polypeptide block copolymers were synthesized. Infrared spectroscopy and differential scanning calorimetry revealed that in the block copolymers both segments undergo phase-mixing, while in polyurethane/polypeptide blend both components undergo phase-separation. Contact angle measurement showed that in the block copolymers polyurethane segments tended to appear on the membrane surface, whereas in polyurethane/polypeptide blend polypeptide components appeared on the membrane surface. In vitro nonthrombogenicity of the block copolymers was similar to that of homopolymers or polymer blends, though adhesion and deformation of platelets were suppressed on the block copolymer membranes.
Details
- Language :
- English
- ISSN :
- 10731199 and 15324184
- Volume :
- 21
- Issue :
- 4
- Database :
- Supplemental Index
- Journal :
- Artificial Cells, Blood Substitutes, and Biotechnology
- Publication Type :
- Periodical
- Accession number :
- ejs13464454
- Full Text :
- https://doi.org/10.3109/10731199309117659