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Humoral Immune Response to the Antigen Administered as an Immune Complex
- Source :
- Immunological Investigations; 1992, Vol. 21 Issue: 7 p623-628, 6p
- Publication Year :
- 1992
-
Abstract
- Antigen (HSA) bound in immune complexes at equivalence with syngeneic anti-HSA antibodies elicit much stronger humoral immune response then soluble HSA. On the other hand, administration of immune complexes formed with xenogeneic (rabbit) anti-HSA antibodies suppressed humoral immune response against HSA, but not against rabbit IgG in mice. We suggest that immunization with antigen bound in immune complex might represent a powerful tool in enhancing humoral immune responses.
Details
- Language :
- English
- ISSN :
- 08820139 and 15324311
- Volume :
- 21
- Issue :
- 7
- Database :
- Supplemental Index
- Journal :
- Immunological Investigations
- Publication Type :
- Periodical
- Accession number :
- ejs13231228
- Full Text :
- https://doi.org/10.3109/08820139209069398