Antiviral Activity of Selected Nucleoside Analogues Against Human Herpes Virus Type 6

Authors :: Reymen, D.
Naesens, L.
Balzarini, J.
Holy, A.
De Clercq, E.
Source :: Nucleosides and Nucleotides; May 1995, Vol. 14 Issue: 3 p567-570, 4p
Publication Year :: 1995
Abstract: HHV-6 was evaluated in vitro for its susceptibility to a broad range of nucleoside analogues. PFA and several acyclic nucleoside phophonates emerged as the most potent inhibitors of HHV-6 replication as monitored by a newly developed immunofluorescence / flow cytometric assay as well as by microscopical evaluation of their inhibitory effect on HHV-6-induced cytopathogenicity.

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