Automated measurement of medial temporal lobe atrophy by computed tomography

ObjectsEvaluation of medial temporal lobe (MTL) atrophy is usually performed by magnetic resonance imaging (MRI). In Japan, however, the availability of computed tomography (CT) is much higher than that of MRI. The evaluation of MTL atrophy using CT may be useful when MRI is unavailable. This project developed a technique to automatically measure MTL atrophy using axial CT imaging and assessed the sensitivity of this method for diagnosing dementia of Alzheimer type (DAT).