Yamogenin in fenugreek inhibits lipid accumulation through the suppression of gene expression in fatty acid synthesis in hepatocytes.

The article discusses a research paper examining the effects of yamogenin on the accumulation of triacylglyceride (TG) in hepatocytes. Topics discussed include expression of fatty acid synthesis-related genes, activation of the liver X receptor (LXR) in luciferase ligand assay, and structural difference between yamogenin and diosgenin.