Evidence of Antagonistic Regulation of Restart from G1 Delay in Response to Osmotic Stress by the Hogl and Whi3 in Budding Yeast.

The article discusses the study done which reveals that the protein kinase Hogl of Saccharomyces cerevisiae is activated by hyperosmotic stress that leads to cell-cycle delay and also informs that the mechanism by which cells restart from cyclin delay remains elusive. Topics discussed include identification of Whi3 as the suppressor mutant, counteraction of Hogl in the restart from G1cyclin delay that was caused by osmotic stress, and measuring the osmotic sensitivity.