Severe Gallbladder Hydrops (Mucocel) Following Obstructive Cholangioma (Biliary Adenoma) in a Cattle.

This article describes a case of obstructive cholangioma (biliary adenoma) followed by severe hydrops (mucocelle of the gallbladder) in an adult bovine. The animal, a six year old female, crossbred cattle, was presented to the necropsy following an acute episode of postpartum septicemia. At necropsy the cholecyst was overdistended, with thick walls and field with 2 liters of clear-mucous content. Proximal to the emergence of the common bile duct, a well-circumscribed, sessile, cauliflower-shaped tumoral mass messuring 4/6 cm, obstruction to bile flow was identified. Cholangioma (cholangiocellular adenoma, biliary adenoma) was histologically diagnosticated bassed on the well-differentiated gland-like structures of the tumor, containing papillary projections covered by cuboidal and prismatic epithelium immunohistochemically positive at cytokeratin 19. In the rest of the gallbladder wall mucinous hyperplasia and discreet mononuclear inflammation was noticed. In this study we described, from our knowledge for the first time in cattle, a case of gallbladder mucocel due to obstructive cholangioma. [ABSTRACT FROM AUTHOR]