Genetic variation in a Japanese population, using the multiplex 24 STRs analysis system.

Abstract: Allele frequency distributions for 24 short tandem repeat (STR) loci were determined using the PowerPlex^R Fusion System (Promega) in 407 Japanese samples. The most informative locus among the 22 STR loci, excluding Amelogenin and DYS391, was Penta E (power of discrimination (PD)=0.98), while the least informative was TPOX(PD=0.831). The 22 loci combined matching probability (MP) was calculated to be 4.13×10⁻²⁶. These parameters indicated the usefulness of this 24 STR analysis in forensic personal identification and parentage testing among Japanese population. [Copyright &y& Elsevier]