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Chemical Synthesis of DNA, RNA, and their Analogues.

Authors :
Caruthers, Marvin
Source :
Chemistry International; Mar/Apr2013, Vol. 35 Issue 2, p8-11, 4p
Publication Year :
2013

Abstract

The article discusses the oligonucleotide synthesis of deoxyribonucleic acid (DNA) and ribonucleic acid (RNA) and their analogues. It mentions that the discovery of phosphoramidite approach for DNA synthesis has been key to the development of several extremely important procedures used in biology, biochemistry and molecular biology. The article also observes that DNA synthesis strategy combined with other core procedures developed in the 1970s and 1980s have reinvigorated biological research.

Details

Language :
English
ISSN :
01936484
Volume :
35
Issue :
2
Database :
Supplemental Index
Journal :
Chemistry International
Publication Type :
Periodical
Accession number :
90517068
Full Text :
https://doi.org/10.1515/ci.2013.35.2.8