Intracerebroventricular transplanted bone marrow stem cells survive and migrate into the brain of rats with Parkinson's disease.

The article presents a study that established Parkinson's disease models by stereotaxically injecting 6-hydroxydopamine into the right substantia nigra compact and ventral tegmental area of rats. The study shows the ability of bone marrow stromal cells in migrating to tissues surrounding the cerebral ventricle via the cerebrospinal fluid circulation. It highlights the role played by bone marrow stromal cells in improving the rotational behavior of rats with induced Parkinson's disease.