Back to Search
Start Over
Effect of Prenatal Selenium Supplementation on Cord Blood Selenium and Lipid Profile.
- Source :
- Pediatrics & Neonatology; Dec2012, Vol. 53 Issue 6, p334-339, 6p
- Publication Year :
- 2012
-
Abstract
- Background: Selenium is an essential trace element and as a component of selenoproteins it plays a key role as an antioxidant. We aimed to evaluate the effect of selenium supplementation during pregnancy on cord blood selenium content and lipid profile. Methods: This trial was performed on 166 eligible women who were randomized to receive 100μg of selenium, as selenium-yeast (Se group) or a placebo-yeast tablet (placebo group). Umbilical cord blood samples were collected at the time of delivery and selenium concentration and lipid profile were measured. Results: Triglyceride levels were found to be significantly higher in the Se group than in the placebo group (p =0.01). However, no significant difference in cord blood selenium was observed between the groups nor were there any significant correlations between cord blood selenium and lipid profile parameters. Conclusion: Our findings suggest that selenium supplementation in pregnant women may be associated with an increased cord-blood triglyceride level, although total cholesterol, low-density lipoprotein and high-density lipoprotein cholesterol levels did not change significantly. The clinical significance of the increased cord triglyceride concentration needs to be evaluated. [Copyright &y& Elsevier]
Details
- Language :
- English
- ISSN :
- 18759572
- Volume :
- 53
- Issue :
- 6
- Database :
- Supplemental Index
- Journal :
- Pediatrics & Neonatology
- Publication Type :
- Academic Journal
- Accession number :
- 84575724
- Full Text :
- https://doi.org/10.1016/j.pedneo.2012.08.008