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Polymorphisms of the coding region of Slc11a1 (Nramp1) gene associated to natural resistance against bovine brucellosis.

Authors :
Paixão, T. A.
Martinez, R.
Santos, R. L.
Source :
Arquivo Brasileiro de Medicina Veterinaria e Zootecnia; Aug2012, Vol. 64 Issue 4, p1081-1084, 4p
Publication Year :
2012

Abstract

The article evaluates the frequency of three novel polymorphisms of bovine Slc11A1 gene, namely p.D321N, p.P356A, and p.Q542del, genotyped in cows with Brucella (B.) abortus in Brazil and its association to the resistant or susceptible phenotypes to brucellosis in cows. All heifers used in the study were serologically negative for brucellosis before challenge. The results indicate a link between Slc11A1 genotype and actual resistance.

Details

Language :
English
Volume :
64
Issue :
4
Database :
Supplemental Index
Journal :
Arquivo Brasileiro de Medicina Veterinaria e Zootecnia
Publication Type :
Academic Journal
Accession number :
83813287