The Role of Urinary Magnesium in Dogs' Rickets Diagnosis.

Indifferently of animal species (including humans) in magnesium deficiencies usually we have one drop of this mineral from bone tissue. This phenomenon is more intense in young animals and is directly correlated with severity of magnesium deficits. The total number of clinical cases was 15 dogs, belong of German Sheppard, Dobermann, Great Dane, Siberian Husky breeds with clinical symptoms of rickets and with ages between 6 to 9 mounts. Group I has included patients with moderate signs of rickets and the group II has included patients with more severe form . Our biochemical analysis was; serum Calcium (SCa), serum Magnesium (SMg), erythrocyte Magnesium (EMg), an inorganic Phosphate (inorg.P), serum Creatinine (SCr) and Alkaline Phosphatase (AP); from urine we determine : urinary Magnesium (UMg), urinary Creatinine (UCr) and Magnesium excretion fraction (MgEF). Median values of seric and erythrocytes Magnesium in both groups were below reference values, but in group 2 were lower than in group 1. Dismagnesiemia is followed by one abrupt decreses in magnesiuria and reduction of excretion fraction of magnesium. This mean that global magnesium reserve is dropping and magnesium activity in cell is deficencity. Rickets osteodystrophia can be associated with slow hipomagnesium tetany. [ABSTRACT FROM AUTHOR]