Reproducibility of the Nicotine Metabolite Ratio in Cigarette Smokers.

The article discusses a research study which examined the reproducibility of the nicotine metabolite ratio (NMR) in cigarette smokers. The study analyzes the stability of NMR in plasma, saliva and blood in various storage conditions, and assesses the agreement between blood plasma, saliva and urine NMRs. Results show the reliability coefficients for stability test of NMR in plasma and saliva, and the reliability coefficient for repeated plasma NMR measurements in smokers.